The global antifreeze proteins market is undergoing a remarkable transformation, driven by rapid innovation in biotechnology, expanding cryopreservation needs, and rising demand across food, medical, and agricultural industries. Valued at USD 13.55 billion in 2024, the market is projected to grow from USD 17.43 billion in 2025 to an impressive USD 167.63 billion by 2034, registering a CAGR of 28.6% from 2025 to 2034.

This explosive growth is largely attributed to the increasing utilization of AFPs in medical and pharmaceutical applications, especially organ and cell cryopreservation, regenerative medicine, organ transplantation, and biobanking. As industries focus on improving cold-chain stability, extending product shelf life, and enhancing biological performance under freezing conditions, antifreeze proteins are becoming indispensable.

What Are Antifreeze Proteins?

Antifreeze proteins are naturally occurring biomolecules found in cold-adapted organisms such as fish, insects, plants, and microorganisms. Their unique ability to inhibit ice crystal growth allows biological tissues to survive below freezing temperatures.

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